Genetic Engineering Report
: Analysis on the Market, Trends, and TechnologiesThe genetic engineering sector has mobilized 2,306 active companies worldwide with total funding of $132.59 billion and annual funding-round growth of 41.26% according to internal trend data. The global market reached USD 1.63 billion in 2024 and is forecast to expand to USD 13.23 billion by 2035 at a 20.97% CAGR, driven by precision gene-editing, synthetic biology, and expanding applications in medicine and agriculture (Top 50 Genetic Engineering Market Size, Research Report 2025). Key enablers include CRISPR-based platforms achieving up to 60% targeted insertion efficiency in human cells through integrase-assisted methods (A new tool to swap out faulty genes), and over 1,200 ongoing clinical trials leveraging gene therapies for rare disorders and oncology (Genetic Engineering Market Size, Share Analysis | CAGR of 6.2%).
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Topic Dominance Index of Genetic Engineering
The Topic Dominance Index combines the distribution of news articles that mention Genetic Engineering, the timeline of newly founded companies working within this sector, and the share of voice within the global search data
Key Activities and Applications
- Precision gene editing using CRISPR-Cas9 for therapeutic interventions and agricultural improvements (Top 50 Genetic Engineering Market Size, Research Report 2025).
- Widespread gene therapy development, with over 1,200 in vivo clinical trials targeting genetic diseases and cancers (Genetic Engineering Market Size, Share Analysis | CAGR of 6.2%).
- Synthetic biology for climate-resilient and high-yield crops, reducing reliance on chemical pesticides (Top 50 Genetic Engineering Market Size, Research Report 2025).
- Development of bio-based industrial products, including biofuels and biodegradable materials via engineered microbial strains (Genetic Engineering Market Size, Share Analysis | CAGR of 6.2%).
Emergent Trends and Core Insights
- Integration of artificial intelligence for predictive design of genetic constructs, accelerating therapeutic candidate discovery (Genetic Engineering Market Size to Hit USD 2.94 Billion by 2034).
- Expansion of non-cutting gene insertion techniques (e.g., base editing and PASTE integrase systems) to minimize off-target effects.
- Growing emphasis on scalable and sustainable DNA synthesis platforms to meet demand for large-scale genome engineering.
- Shifting regulatory landscapes facilitating faster market entry for gene-edited crops compared to traditional GMOs, broadening adoption in agriculture.
- Increasing collaborations between academic institutions and biotech firms to translate laboratory advances (e.g., integrase-based PASTE) into clinical therapies (A new tool to swap out faulty genes).
Technologies and Methodologies
- CRISPR-Cas9 platforms enabling targeted gene knockout, knock-in, and multiplexed edits across diverse cell types.
- Base editors for single-nucleotide conversions without double-strand breaks, improving precision in point-mutation correction.
- PASTE (Programmable Addition via Site-specific Targeting Elements) combining CRISPR-Cas9 targeting with integrases for efficient large-fragment integration (5–60% success in human cells) (A new tool to swap out faulty genes).
- Enzymatic DNA synthesis (dbDNA™) for rapid, scalable production of long DNA constructs to fuel cell and gene therapies (Touchlight’s Enzymatic DNA Technology).
- Computational bioinformatics pipelines for in silico design and optimization of genetic circuits and metabolic pathways.
Genetic Engineering Funding
A total of 837 Genetic Engineering companies have received funding.
Overall, Genetic Engineering companies have raised $136.7B.
Companies within the Genetic Engineering domain have secured capital from 3.6K funding rounds.
The chart shows the funding trendline of Genetic Engineering companies over the last 5 years
Genetic Engineering Companies
- GenEdit: Focused on overcoming delivery barriers for genetic medicines, GenEdit’s NanoGalaxy platform screens thousands of non-viral polymer nanoparticles to identify those capable of delivering gene editors to specific tissues, enabling therapeutic options previously unattainable (GenEdit).
- GreenGene: Specializes in chloroplast and mitochondrial gene editing, targeting RuBisCo to enhance photosynthetic efficiency, with the dual goal of boosting crop yields and generating carbon credits through engineered plants (GreenGene).
- GeneNeer: Develops precision gene-editing tools for climate-resilient crop breeding, leveraging Superlines and tissue-specific silencing to rapidly produce pest- and virus-resistant varieties for global food security (GeneNeer).
- ATG:biosynthetics GmbH: Offers integrated synthetic biology solutions, combining multi-gene recombineering, bespoke expression systems, and bioinformatics (EvoMAG) to design and assemble complex genetic constructs for drug discovery and industrial biotechnology (ATG:biosynthetics).
- Hunterian Medicine: Pioneers CRISPR delivery via a single-AAV “2-for-1” genetic element, enabling efficient in vivo editing to correct DNA mutations in gene-editing therapies for inherited diseases (Hunterian Medicine).
Gain a competitive edge with access to 2.5K Genetic Engineering companies.
2.5K Genetic Engineering Companies
Discover Genetic Engineering Companies, their Funding, Manpower, Revenues, Stages, and much more
Genetic Engineering Investors
Leverage TrendFeedr’s sophisticated investment intelligence into 4.1K Genetic Engineering investors. It covers funding rounds, investor activity, and key financial metrics in Genetic Engineering. investors tool is ideal for business strategists and investment experts as it offers crucial insights needed to seize investment opportunities.
4.1K Genetic Engineering Investors
Discover Genetic Engineering Investors, Funding Rounds, Invested Amounts, and Funding Growth
Genetic Engineering News
TrendFeedr’s News feature provides a historical overview and current momentum of Genetic Engineering by analyzing 30.7K news articles. This tool allows market analysts and strategists to align with latest market developments.
30.7K Genetic Engineering News Articles
Discover Latest Genetic Engineering Articles, News Magnitude, Publication Propagation, Yearly Growth, and Strongest Publications
Executive Summary
Genetic engineering is maturing into a diverse ecosystem of precision editing tools, scalable synthesis platforms, and AI-driven design methods that collectively accelerate innovation across therapeutics, agriculture, and industrial biotechnology. With strong annual funding growth and a rapidly expanding market, the field’s strategic focus on delivery technologies, safety-enhanced insertion methods, and sustainable DNA production will define competitive differentiation. Stakeholders should prioritize flexible delivery platforms and integrative bioinformatics pipelines while monitoring regulatory shifts that favor gene-edited crops. Continued cross-sector partnerships, especially between technology-developers and clinical research, will be essential to translate cutting-edge methodologies into real-world impact and maintain momentum in addressing global health and sustainability challenges.
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